CLINDAGEL (clindamycin phosphate) gel, 1% is indicated for topical application in the treatment of acne. CLEOCIN T Topical Lotion containing clindamycin phosphate equivalent to 10 mg clindamycin per milliliter is available in the following size: 60 mL plastic squeeze bottle—NDC 0009-3329-01. Diagnosis is by examination. AM: Cerave Acne Foaming Cleanser (4% benzoyl peroxide) Clindagel (1% clindamycin. 5%: For the topical treatment of acne vulgaris. September 13, 2021. 4 out of 10 from a total of 135 reviews for the treatment of Acne. Lie on your back with knees bent or in any comfortable position. the topical antimetabolite,________, inhibits cancer cells from synthesizing DNA and is used to treat basal cell and squameous cell cancers on. 62% of reviewers reported a positive experience, while 27% reported a negative experience. Keep out of your child’s mouth, nose, and eyes (may burn). It is usually applied twice a day, in the morning and evening. Use our SingleCare savings offer to get great discounts on Cleocin-T at participating pharmacies near you. This may dry your skin and make your acne worse. Filter by condition. Adapalene + Clindamycin is a combination of two medicines: Adapalene and Clindamycin, which treats pimples (acne). Call your doctor for medical advice about side effects. clindamycin topical may also be used for purposes not listed in this medication guide. A 12-week study compared Clindagel™, a unique water-based gel formulation of clindamycin phosphate 1%, administered once daily, and Cleocin T®, a slightly different gel formulation indicated for twice-daily use, in the treatment of acne vulgaris. Lowering blood pressure helps prevent strokes, heart attacks, and kidney problems. Solaris Pharma Receives Approval for First Generic Version of Clindagel Solaris Pharma Receives Approval for First Generic Version of Clindagel BRIDGEWATER, N. Generic name: clindamycin topical Medically reviewed by Drugs. If any of these effects last or get worse, tell your doctor. Diagnosis is clinical, rarely aided by culture. Clindamycin is usually applied twice a day, once in the morning and once in the evening, except for the foam and 1 brand of gel (Clindagel®) which are applied once a day. As a guide, Clindagel topical gel 1% will cost around $1,900 for 75 milliliters. Ways to save on Clindacin P. Yes there is. It occurs when. Serious side effects; Other side effects; Professional info; Note: This document contains side effect information about clindamycin topical. clindamycin topical may also be used for purposes not listed in this medication guide. The gel contains allantoin, carbomer 974P, methylparaben, polyethylene glycol 400, propylene glycol, sodium hydroxide, and purified water. Prices start at $11. How to say clindagel in English? Pronunciation of clindagel with 1 audio pronunciation and more for clindagel. Informação médica para Clindagel, incluindo sua dosagem, usos, colaterais, efeitos, interações, imagens e avisos. You may be able to lower your total cost by filling a greater quantity at one time. Prescription only. It is unlikely that using clindamycin increases the chance of birth defects. Compare prices and print coupons for Clindamycin (Generic Cleocin, Cleocin T, Clindagel, and Evoclin) and other drugs at CVS, Walgreens, and other pharmacies. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Get the full list here, including natural retinoids. Prescription only. Shake lotion well before use. MANIFESTACIONES Y MANEJO DE LA SOBREDOSIFICACIÓN O INGESTA ACCIDENTAL. Clindamycin is available under different brand names and as a combination medication. 99. For topical use only, not for oral, ophthalmic, or intravaginal use. Fill a 90-Day Supply to Save. Because acne takes time to treat, this usually. acnes) bacteria that can lead to. This medicine works by slowing or stopping the growth of bacteria. How to say Clindagel Gel in English? Pronunciation of Clindagel Gel with 1 audio pronunciation and more for Clindagel Gel. Medical professionals, medical facility employees 855. LEYENDAS DE PROTECCIÓN. Call us at (833) 862-8727, 8 AM to 5 PM ET for more information. Clindamycin should only be applied to intact skin. Taro markets a broad range of prescription and over-the-counter products in the United States. Clindagel was safe and effective and equivalent to Cleo. methotrexate levels, risk of serious infection, myelosuppression, nephrotoxicity, other adverse effects; may decr. Generic name: CLINDAMYCIN PHOSPHATE 1g in 10mL. Clindamycin (Cleocin-T) can make your skin more sensitive to sunlight. Clindamycin is an antibiotic which works by stopping the growth of bacteria. chevron_right. Anthrax is caused by the gram-positive Bacillus anthracis, which are toxin-producing, encapsulated, facultative anaerobic organisms. Carroll, PharmD Contributions by: Drs. It works by slowing down your body's defense system (immune. Know what side effects of Clindagel to expect. hydrocortisone. Uses. It binds to the 50S subunit of the ribosome, thus inhibiting bacterial protein synthesis. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. CLINDAGEL SUMMARY Clindagel ® (Clidamycin phosphate gel) topical gel, 1%, a topical antibiotic, contains clindamycin phosphate, USP, at a concentration equivalent to 10 mg clindamycin per gram in a gel vehicle consisting of carbomer 941, methylparaben, polyethylene glycol 400, propylene glycol, sodium hydroxide, and purified water. It belongs to a group of medications called antibiotics. Do not store in direct sunlight. Clobetasol. Follow the directions on your prescription label carefully, and ask your doctor or. 2. Folliculitis decalvans (FD) is a rare, chronic cicatricial (scarring) alopecia that occurs in adults and classically presents as an expanding patch of alopecia with peripheral pustules on the scalp ( picture 1A-B ). The product is distributed in 2 packages with assigned NDC codes 16781-462-06 6. Coverage of drugs is first determined by the member’s pharmacy or medical benefit. Cleocin T side effects (more detail)Solaris Pharma Corporation recently announced the company has received an abbreviated new drug application (ANDA) approval from the US FDA for the first generic version of Clindagel (clindamycin phosphate EQ 1%). BRIDGEWATER, N. ALTRENO® (tretinoin) Lotion, 0. It contains adapalene, a third generation retinoid that can help treat and prevent acne. show all brand names. The infant's stools were reported to have normal flora and the stools became guaiac negative 24 hours after discontinuation of breastfeeding. Treatment is with antibiotics. There is also a bullous form of erysipelas. FDA Approved Indications: Aczone Gel 5%, Epiduo Forte: For the topical treatment of acne vulgaris. RECOMENDACIONES SOBRE ALMACENAMIENTO. Amlodipine is a prescription medication that is used with or without other medications to treat high blood pressure. If you have ever had any of these health problems: Crohn’s disease, certain other stomach or bowel problems (colitis, enteritis), or severe bowel problems while taking an antibiotic (severe diarrhea, bowelMaterial Safety Data Sheet Material Name: Clindagel® clindamycin phosphate topical gel equivalent to 1% clindamycin Page 1 of 6 Issue Date: 12/10/13 Revision: 1. Post-Deductible. CLINDAGEL (clindamycin phosphate) topical gel, 1%, a topical antibiotic, contains clindamycin phosphate, USP, at a concentration equivalent to. The generic name of Clindagel is clindamycin. Amlodipine belongs to a. 1981;57 (1):51-8. Schau dir das neueste Video von SELIN🌶🦖. CLINDAGEL (clindamycin phosphate gel) topical gel, 1%, a topical antibiotic, contains clindamycin phosphate, USP, at a concentration equivalent to 10 mg clindamycin per gram in a gel vehicle consisting of carbomer 941, methylparaben, polyethylene glycol 400, propylene glycol, purified water, and sodium hydroxide. itching of treated skin. com. CLINICAL STUDIES. Pertenece a la clase de medicamentos agentes tópicos para el acné y antiinfecciosos vaginales y esta se usa para el tratamiento de: acné, vaginitis bacteriana y dermatitis perioral. com. Dosage form: gel. Seek medical care or call 911 at once if you have the following serious side effects: Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or. Clindagel ® (clindamycin phosphate gel) Topical Gel, 1% Prescribing Information. Use is not recommended and a decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother. A 1% clindamycin phosphate gel similar to CLINDAGELcaused a statistically significant shortening of the median time to tumor onset in a study in hairless mice in which tumorsClindamycin, Erythromycin Topical Limit, Post PA Policy UDR 04-2023. Use enough to cover the entire affected area lightly. 0280. Adapalene is a form of vitamin A which prevents accumulation of the sebum (skin’s natural oil), unblocks the pores and allows natural exfoliation of the outer layers of skin. When including an antibiotic in your acne treatment plan, your dermatologist will prescribe it for the shortest time possible. Clindamycin phosphate yellow/white bottle from Dermatologistit, very watery,takes forever to dry (into a white, chalky texture), needs to be shaked, can't te. temporary hair loss. ACNE AGENTS, TOPICAL section updated 4-22-2019 Preferred Nonpreferred AZELEX BENZOYL PEROXIDE 10% WASH OTC (TOPICAL) BENZOYL PEROXIDE 3% CLEANSER OTC (TOPICAL)Giant Pharmacy. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Metronidazole topical. Amlodipine is used with or without other medications to treat high blood pressure. $205 retail. 30 days (1 bottle of 75 milliliters) Supply. clindamycin topical may also be used for purposes not listed in this medication guide. 23, 2021 (GLOBE NEWSWIRE. Title: 50-782 Clindagel Statistical Review Created Date: 7/6/2004 2:17:00 PMCommon Brand(s): Cleocin T, Clinda-Derm This medication is used to treat acne. Satisfaction. Its use to treat certain infections, such as toxoplasmosis, is “off label” or “extra. You may report side effects to FDA at 1-800-FDA-1088. Bacteria can spread from an infected lower tooth to the tissue under and around the tongue. BRIDGEWATER, N. This medication is used to treat acne. Several human studies as well as animal studies have not shown an increased chance of birth defects. Abdominal or stomach cramps, pain, and bloating (severe) diarrhea (watery and severe), which may also be bloody. white, shiny patches at the top of the penis. It is used to treat acne (a common skin condition where the pores of your skin become blocked by hair, oily substance, bacteria, and dead skin cells). clindamycin topical may also be used for purposes not listed in this medication guide. Accutane can cause many side effects. clindamycin topical may also be used for purposes not listed in this medication guide. com. This is not a complete list of side effects and others may occur. 1% as an OTC product. Manfaat cindala gel dapat mengobati beberapa jenis infeksi berat. com discount card which is accepted at most U. O. Medicine home elevators Cleocin T, Clindagel, ClindaMax, ClindaReach Pledget, Evoclin (clindamycin topical ointment), incorporates medicine pictures, adverse reactions, medication communications, guidelines to be used,. Few studies have directly compared combined formulat. or I. diarrhea, stomach pain, joint pain, vaginal itching or discharge, skin rash or itching, heartburn, sore throat, or. Ihr Schicksal bewegte die Menschen in ganz Deutschland: Selin E. To help you remember to use clindamycin and benzoyl peroxide gel, apply it at around the same times every day. 9 out of 10 from a total of 230 ratings on Drugs. In humans, infection is typically acquired through the skin. 5% (Cortisporin®)Long-Acting Reversible Contraception (LARC): Intrauterine Device (IUD) and Implant. Entrega rápida en todo el mundo. Refissa - Free Shipping. Clinda 1% Gel has some common side effects such as burning. Accounts Receivable 800. Manufacturer Coupon. Amazon Prime members get additional benefits including FREE 2-Day Delivery and low prices on medications. skin rash or irritation around your mouth. Clindamycin topical may cause serious side effects. Whether you decide to continue your tretinoin or switch to one of its alternatives, SingleCare coupons may help lower the cost at participating pharmacies. Clindamycin Phosphate (ab2) (Generic for Clindagel) Gel · 1% · 30-day supply. Topical combination therapy has shown superior efficacy compared to monotherapy, especially when combined with retinoids. Avoid using other harsh skin products that can further dry or irritate your skin. 12K Followers, 63 Following, 67 Posts - See Instagram photos and videos from (@selinsudeguelofficial) The latest tweets from @Selinsudeguel See full list on drugs. Patients with insurance that doesn't cover Clindagel will pay a $65 copay. Irregular heartbeat. oily skin. Hold the filled applicator and slowly insert the tip into your vagina as far as it will go. Condition. clindamycin topical + methotrexate if oral methotrexate use, consider alternative or monitor CBC, renal fxn: combo may incr. Put a thin layer on the affected skin. 5% strength is specifically indicated in patients 9 years of age and older. High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood. Periorificial dermatitis includes perioral dermatitis or periocular dermatitis alone, or in association. CLINDAGEL is contraindicated in patients with a history of hypersensitivity to. Lie on your back with knees bent or in any comfortable position. Data sources include Micromedex (updated 5 Nov 2023), Cerner Multum™. Get free savings. Differin, Tazorac, Aklief, Epiduo, and Arazlo are some tretinoin alternatives. P. , Aug. V. FAQs Progestin-Only Hormonal Birth Control: Pill and Injection. Protect from freezing. PRESENTACIÓN. Para la clindamicina tópica, las marcas comerciales más conocidas son: Cleocin T, Clindamax, Clindagel y Clindesse. Clindagel Prices -. Drug Review Package. , scarring, poor self-image, depression) and results in. What are the possible side effects of Clindagel Topical? Get emergency medical help if you have any signs of an allergic reaction to Clindagel Topical: hives; difficult breathing; swelling of your face, lips, tongue, or throat. In rare cases, bromhidrosis may become pathologic if it is particularly overpowering or if the bromhidrosis significantly interferes with the lives of the affected individuals. symptoms of a fungal (yeast) infection --vaginal itching or discharge. Food and Drug Administration (“FDA” or “Agency”) for the first generic version of Clindagel®. mupirocin. 7387Postpartum endometritis is uterine infection, typically caused by bacteria ascending from the lower genital or gastrointestinal tract. changes in bowel habits (especially in older adults). impetigo can be treated with. 1% Strength. The structural formula is represented below: The chemical name for clindamycin hydrochloride is Methyl 7-chloro-6,7,8-trideoxy-6-Use on your child’s skin only. Store at controlled room temperature 20° to 25°C (68° to 77°F) [see USP]. In a contact sensitization study, four of the 200 subjects appeared to develop suggestive evidence of allergic contact sensitization to Clindagel ® . Trademarks, brands, logos, and copyrights are the property of their respective owners. Solaris Pharma Corporation received the FDA approval, while its manufacturing partner Cosette will develop generic Clindagel in the United States. Common side effects of Clindacin ETZ may include: burning, itching, dryness, peeling or redness of treated skin; or. Hold the filled applicator and slowly insert the tip into your vagina as far as it will go. BRIDGEWATER, N. acnes. It comes in oral, injectable, suppository, lotion, cream, and gel forms, depending on the use. Prior Auth Protocol. The average price of Cleocin-T is around $166 for a supply of 30 g of 1% topical gel. Clindagel Prices, Coupons and Patient Assistance Programs. Improvements may take anywhere from 2 to 12 weeks. Tell your doctor if any of these symptoms are severe or do not go away: dry or peeling skin. RLD. swollen hair follicles. Prescription only. Leave the plunger inside the applicator. management ⬇️. Prescriber’s NPI Enter the prescribing practitioner’s National Provider Identification (NPI) numberAnthrax. show all brand names. You should apply the medicine to the whole area usually affected by acne, not just to the pimples themselves. La información mostrada corresponde a la última IPPA (información para prescribir amplia) proporcionada por el laboratorio, por lo que podría no estar actualizada. These medications may be counterfeit and potentially unsafe. FAQs Combined Hormonal Birth Control: Pill, Patch, and Ring. 08 Jul, 2014, 08:00 ET. Retail price for 30-day supply. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Brand names: Clindagel, Cleocin T, Clindesse, Cleocin Vaginal, Clindacin,. PATIENT & CAREGIVER EDUCATION Clindamycin (Topical This information from Lexicomp explains what you need to know about this medication, including what it’sSide effects of BenzaClin Topical Gel include: dry skin, severe skin redness, burning, itching or tingly feeling, skin peeling, irritation, and. It works by relaxing blood vessels so blood can flow more easily. Be sure to avoid sunlamps and tanning booths too. Diclofenac Cap 35mg, Zorvolex : celecoxib, diflunisal, etodolac, flurbiprofen, ibuprofen, indomethacin, ketoprofen, ketorolac, meclofenamate, meloxicam, nabumetone. Hidradenitis suppurativa is currently thought to be a chronic inflammatory condition of the hair follicle and associated structures. Use our SingleCare discount card to save money on Clindagel at participating pharmacies near you. 1. Clindamycin is the generic version of Cleocin-T. Clindagel is a semisynthetic antibiotic derived from lincomycin. Take an antibiotic for the shortest time possible. Clindamycin topical for Perioral Dermatitis User Reviews. The most common manifestation is an acute but slowly evolving localized cellulitis. It works by reducing acne-causing bacteria. pimples. The average price of Cleocin-T is around $166 for a supply of 30 g of 1% topical gel. Deje de usar clindamycin topical y llame de inmediato a su médico si usted tiene: enrojecimiento severo, picazón, o sequedad de la piel que ha recibido tratamiento; o. fluorouracil. Niacinamide/Turmeric. changes in the color of treated skin. Tier 1. Clindagel Topical phosphate IM administration should be used undiluted. dolor severo de estómago, diarrea que es acuosa o con sangre (así ocurra meses después de su última dosis). Therefore, the Centre of Evidence of. Keep using this drug as you have been told by your child’s doctor or other health care provider, even if your child’s signs get better. Clindamycin topical side effects. Leave the plunger inside the applicator. resistance has been demonstrated between clindamycin and erythromycin. A 1% clindamycin phosphate gel similar to CLINDAGELcaused a statistically significant shortening of the median time to tumor onset in a study in hairless mice in which tumors Clindamycin, Erythromycin Topical Limit, Post PA Policy UDR 04-2023. Treatment depends on stage. Clindagel ® (clindamycin phosphate) – First-time generic . Generics should be considered the first line of prescribing. pharmacies. It is available as a foam, gel, lotion, solution. Stop using clindamycin topical and call your doctor at once if you have: severe stomach pain, diarrhea that is. 1% (Garamycin®) gentamicin ointment 0. Acute mediastinitis usually results from esophageal perforation or occurs after median sternotomy. Fourth St. Wisconsin Medicaid, BadgerCare Plus Standard, and SeniorCare Preferred Drug List – Quick Reference Effective 01/01/2023 Page 2 of 13 Brand Before Generic DrugSialadenitis. Acute calcific tendinitis and rheumatoid arthritis can restrict motion and cause pain in the tendon sheath but can usually be differentiated from infectious flexor tenosynovitis by a more gradual onset and the absence of some Kanavel signs. Clean affected part before use. Call your doctor for medical advice about side effects. temporary hair loss. $ 129. The average cost for 1 Bottle, 60ml of 1% each of the generic (clindamycin phosphate) is $88. perfringens) 1. 3,96 Resorcinol 15% cream, a keratolytic and antiseptic, was studied in 12 women with Hurley stage I or II disease twice daily for HS flares and daily between flares; it reduced pain. The lotion contains cetostearyl alcohol (2. impetigo can be treated with. The foam and one brand of the gel (Clindagel ®) are usually applied once a day. High fever, chills, and malaise frequently accompany erysipelas. high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss). Prescribed for Photoaging of the Skin, Acne, Lichen Sclerosus. For more information, see the “Side. 7 g/day I. Perioral dermatitis describes an eruption around the mouth and nose. Common side effects of clindamycin and tretinoin may include: mild skin irritation, dryness or peeling; mild skin redness; or. Click on a tab below…. Symptoms are uterine tenderness, abdominal or pelvic pain, fever, malaise, and sometimes discharge. 00. . 69% of reviewers reported a positive experience, while 21% reported a negative experience. Buy Clindagel online or toll-free: 1. Some dosage forms listed on this page may not apply to the brand name Clindacin. It has antiacne and antibacterial activity. Clindagel Interactions. RETIN-A Gel, Cream and Liquid, containing tretinoin are used for the topical treatment of acne vulgaris. Clindagel: prescribed as part of treatment for acne. What is Clindagel Clindamycin is an antibiotic. docx This document contains confidential and proprietary information of CVS Caremark and cannot be reproduced, distributed or printed without writtenWhy Legal Pot Makes This Physician Sick. (. RECOMENDACIONES SOBRE ALMACENAMIENTO. Erythromycin and clindamycin are two good options. The typical out-of-pocket price of Clindamycin-Tretinoin without health insurance is $438. Clindagel Description. Topical clindamycin is an antibiotic used to treat severe acne. 375; noninflammatory lesions, P =. clindamax (cleocin) 150 mg el precio mas bajo y comprar barato online clindamax (cleocin) 150 mg, genérico clindamax, clindamax (cleocin) venta en mexico, clindamax. Without insurance. 00 Clindagel Dosage. spider veins. If using pledgets (swabs), take pledget from the foil just before use. Stop using clindamycin topical and call your doctor at once if you have: severe stomach pain, diarrhea that is. But by the next afternoon, the cyst is swollen and painful once again. com PDL Prior Authorization Drugs identified as “non-preferred” require a PDL prior authorization. , Aug. Other side effects of Clindam (clindamycin) include. Clindagel is a lincosamide antibiotic used in the treatment of infections caused by susceptible microorganisms. The actual type of inflammatory cells can vary and may be dependent on the etiology of the folliculitis, the stage at which the biopsy specimen was obtained, or both. The hair loss is permanent, but certain hair loss. Clindamycin is an antibiotic which works by stopping the growth of bacteria. show all brand names. GoodRx is not sponsored by or affiliated with any of the third-party brands identified. Make sure to dry well. Clindamycin topical User Reviews & Ratings. However, it is not usually recommended for children aged less than eight or pregnant women in the last half of. b. Diagnosis is clinical. Wash your hands before and after use. Antibiotics, steroids and other treatments can help ease inflammation and prevent more hair loss. Clindagel is a topical antibiotic used to treat acne. It also has antibacterial properties. Erysipelas should not be confused with erysipeloid , a skin infection caused by Erysipelothrix rhusiopathiae. It isn't clear whether antiseptic solutions or creams can help. 10903 New Hampshire Avenue Silver Spring, MD 20993 Ph. com. Clindagel prevents bacteria from growing on the skin. inhibited, decr. Compare prices and print coupons for Clindagel (Clindamycin) and other drugs at CVS, Walgreens, and other pharmacies. 31/day. Before applying this medicine, thoroughly wash the affected areas with warm water and soap, rinse well, and pat dry. Post-Deductible. The product's dosage form is gel and is administered via topical form. Clindagel may also be used for purposes not listed in this medication guide. clindamycin topical + methotrexate if oral methotrexate use, consider alternative or monitor CBC, renal fxn: combo may incr. Prescribed for Perioral Dermatitis, Bacterial Vaginosis, Acne. Arazlo® (tazarotene) Lotion, 0. Common side effects of clindamycin and tretinoin may include: mild skin irritation, dryness or peeling; mild skin redness; or. est. Clindagel was safe and effective and equivalent to Cleo. Common carvedilol side effects may include: weakness, dizziness;Doctors commonly prescribe drugs on the following acne medication list: Azelaic acid (Azelex, Finacea) is an acid keratolytic. Add to Medicine Chest. Ini termasuk acne vulgaris yang disebabkan oleh hiperproliferasi, epidermis folikular, inflamasi, produksi keringat yang berlebihan, dan aktivitas bakteri P. LEYENDAS DE PROTECCIÓN. a. , Aug. BUREAU FOR MEDICAL SERVICES WEST VIRGINIA MEDICAID PREFERRED DRUG LIST WITH PRIOR AUTHORIZATION CRITERIA This is not an all-inclusive list of available covered drugs and includes onlyBuy Clindagel, Generic Clindamycin and Canada prescription drugs from our generic pharmacy Blue Sky. q 6 hours, or (for other than C. A difference is metronidazole is taken orally and clindamycin phosphate vaginal cream is used topically (on the skin). a. Periorificial dermatitis includes perioral dermatitis or periocular dermatitis alone, or in association. Set Price Alert. It is often used to treat wounds, pyoderma, abscesses, bone and dental infections, and toxoplasmosis. a. A list of all FDA-approved abbreviated new drug applications for drug products that received a Competitive Generic Therapy designation under section 506H of the Federal Food, Drug, and Cosmetic Act.